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. 2018 Oct 15;10(10):e3452. doi: 10.7759/cureus.3452

Table 1. Summary of spontaneous pneumomediastinum cases in pregnancy.

Author Age Parity Stage of Labor Duration of Labor (hours) Duration of Pregnancy (weeks) Treatment
Crean et al. 1981 [5] 22 y/o 1st 2nd stage 12 N/A Oxygen
Hubbert et al. 1981 [13] 17 y/o N/A 2nd stage N/A N/A Oxygen, fentanyl, diazepam, & succinycholine
18 y/o N/A 2nd stage N/A N/A Oxygen
Karson et al. 1984 [14] 20 y/o 1st  1st stage N/A 9 Pyridoxine 2x daily
20 y/o 1st  1st stage N/A 42 None
Jensen et al. 1987 [15] 24 y/o 1st 2nd stage 10.5 41 Oxygen
Ramirez-Rivera et al. 1990 [16] 15 y/o 1ST 2nd stage 14 N/A Oxygen
Jayran-Nejad et al. 1993 [17] 18 y/o 1st 2nd stage 15.6 42 Analgesia
Seidl et al. 1994 [18] 23 y/o 2nd  N/A N/A 42 None
Gocmen et al. 1997 [19] 17 y/o 1st  N/A 11 39 Symptomatic management & monitoring
Shyamsunder et al. 1999 [20] 18 y/o 2nd  2nd stage N/A 6 None
Gorbach et al. 1997 [21] 21 y/o N/A 2nd stage 4 9 IV Fluids, Promethazine
Raley et al. 1997 [22] N/A N/A N/A N/A 41 Oxygen
Dhrampal et al. 2001 [23] 36 y/o N/A 2nd stage N/A 37 Oxygen & analgesia
Sutherland et al. 2002 [24] 32 y/o 1st  2nd stage 8 N/A None
22 y/o 1st  2nd stage 13 N/A None
Miguil et al. 2004 [25] 19 y/o N/A 2nd stage N/A 40 Oxygen & analgesia
Balkan et al. 2006 [26] 25 y/o 1st  2nd stage N/A 36 Oxygen
Bonin et al. 2006 [10] 27 y/o 1st  2nd stage 6 38 Lorazepam for anxiety; anxiolytics for dyspnea
North et al. 2006 [27] 32 y/o N/A 2nd N/A N/A Laxatives
Yadav et al. 2008 [28] 21 y/o 1st 2nd stage 1.3 N/A Oxygen & analgesics
Mahboob et al. 2008 [9] 24 y/o N/A 2nd stage N/A 39 Oral antibiotics
Zapardiel et al. 2009 [29] 29 y/o 1st 4th stage – only time 7 39 Oxygen
Speksnijder et al. 2010 [30] 15 y/o N/A 2nd stage N/A 28 Insulin, fluid, & potassium supplementation
Beynon et al. 2011 [31] 18 y/o 1st   2nd stage 4.3 39 + 2 Antibiotics & analgesia
Wozniak et al. 2011 [32] 20 y/o N/A 2nd stage N/A 41 Observation
Shrestha et al. 2011 [33] 19 y/o 1st  2nd stage N/A 36 None
Kuruba et al. 2011 [34] 32 y/o 2nd  2nd stage 1.5 40 None
McGregor et al. 2011 [35] 27 y/o 1st  2nd stage 1.5 40 Oxygen & analgesia
Khoo et al. 2012 [36] 33 y/o 1st  2nd stage 12 40 Analgesia & best rest
Kouki et al. 2013 [37] 23 y/o 1st  2nd stage 9 40 Oxygen & analgesics and sedatives
Cho et al. 2015 [38] 28 y/o 1ST 2nd stage 5 36 Oxygen & analgesics
Scala et al. 2016 [39] 30 y/o N/A N/A N/A 40 None
Nagarajan et al. 2017 [40] 30 y/o N/A 2nd stage N/A 41 Observation
Berdai et al. 2017 [41] 22 y/o 1ST 2nd stage 2H 40 Oxygen