Table 4.
Adjusted* Associations of Pubertal Age and Magnitude of Peak Height Velocity with Risk of Asthma Symptoms and Wheezing at Ages 16 and 23 Years by Sex
| Pubertal Height Growth | Adolescence: Age, 16 Years |
Early Adulthood: Age, 23 Years |
||||||
|---|---|---|---|---|---|---|---|---|
| Females |
Males |
Females |
Males |
|||||
| Adjusted OR (95% CI)* | P Value† | Adjusted OR (95% CI)* | P Value† | Adjusted OR (95% CI)* | P Value† | Adjusted OR (95% CI)* | P Value† | |
| Asthma symptoms |
n = 1,703 |
n = 1,278 |
n = 1,758 |
n = 924 |
||||
| APV | 0.72 (0.59–0.87) | 7 × 10−4 | 0.85 (0.68–1.07) | 0.171 | 0.84 (0.67–1.07) | 0.156 | 0.85 (0.56–1.28) | 0.433 |
| PV | 0.79 (0.66–0.94) | 0.010 | 0.81 (0.66–0.98) | 0.033 | 0.77 (0.61–0.96) | 0.022 | 0.83 (0.59–1.17) | 0.277 |
| |
||||||||
| Wheezing |
n = 2,120 |
n = 1,564 |
n = 2,041 |
n = 1,128 |
||||
| APV | 0.89 (0.75–1.05) | 0.152 | 0.97 (0.79–1.20) | 0.799 | 0.79 (0.66–0.94) | 0.009 | 0.88 (0.68–1.15) | 0.357 |
| PV | 0.88 (0.76–1.03) | 0.101 | 0.99 (0.82–1.18) | 0.892 | 0.78 (0.66–0.93) | 0.006 | 0.87 (0.69–1.10) | 0.247 |
Definition of abbreviations: APV = age at peak height velocity; CI = confidence interval; OR = odds ratio; PV = peak height velocity.
*
Adjusted for: parity; maternal history of asthma or allergy; maternal smoking during pregnancy; birth weight; exposure to smoke from birth to 8 years of age; and smoking status.
†
P values from Wald test.