Table 1. Participant demographic and disease characteristics at baseline (mITT population).
| Parameter | Mg–vit B6 combination (N = 132) | Mg (N = 132) | Total (N = 264) |
|---|---|---|---|
| Age (years), mean (SD) | 31.2 (8.4) | 32.1 (8.6) | 31.6 (8.5) |
| Sex female, n (%) | 98 (74.2) | 97 (73.5) | 195 (73.9) |
| BMI, kg/m2, mean (SD) | 23.0 (3.0) | 22.9 (2.7) | 23.0 (2.8) |
| BMI category, n (%) | |||
| Normal (18.5–<25 kg/m2) | 101 (76.5) | 102 (77.3) | 203 (76.9) |
| Overweight (25–<30 kg/m2) | 31 (23.5) | 30 (22.7) | 61 (23.1) |
| Systolic blood pressure (mmHg), mean (SD) | 118.2 (13.4) | 116.7 (11.1) | 117.4 (12.3) |
| Diastolic blood pressure (mmHg), mean (SD) | 73.9 (9.1) | 72.8 (8.3) | 73.4 (8.7) |
| Heart rate (bpm), mean (SD) | 68.1 (12.8) | 67.6 (11.6) | 67.9 (12.2) |
| Serum Mga (mmol/L) | |||
| Mean (SD) | 0.80 (0.0) | 0.80 (0.0) | 0.80 (0.04) |
| Median (Min, Max) | 0.80 (0.7, 0.8) | 0.80 (0.7, 0.8) | 0.82 (0.66, 0.84) |
| Erythrocyte Mg (mmol/L), mean (SD) | 1.80 (0.30) | 1.80 (0.40) | 1.83 (0.31) |
| Serum B6 (nmol/L), mean (SD) | 50.6 (68.8) | 46.5 (27.6) | 48.6 (52.3) |
| DASS-42 stress subscale score, mean (SD) | 27.7 (7.3) | 27.6 (7.0) | 27.7 (7.1) |
| DASS-42 total score, mean (SD) | 58.3 (21.3) | 58.4 (20.9) | 58.4 (20.9) |
aAt screening visit;
BMI, body mass index; bpm, beats per minute; DASS, Depression Anxiety Stress Scales; mITT, modified intention-to-treat; Mg, magnesium; SD, standard deviation; Vit B6, vitamin B6.