Table 1.
Baseline Characteristics by CHG Exposure
| CHG-exposed n=18 |
Non-exposed n=22 |
All n=40 |
P-value | |
|---|---|---|---|---|
| Male, n (%) | 8 (44.4%) | 13 (59.1%) | 21 (52.5%) | 0.36 |
| Gestational age in weeks, mean ± SD | 32.8 ± 6.0 | 35.2 ± 5.1 | 34.1 ± 5.6 | 0.17 |
| Birth weight in grams, mean ± SD | 2146.4 ± 1213.5 | 2484.3 ± 1047.5 | 2332.2 ± 1123.3 | 0.35 |
| Inborn, n (%) | 11 (61.1%) | 15 (68.2%) | 26 (65.0%) | 0.64 |
| C-section, n (%) | 11 (61.1%) | 15 (68.2%) | 26 (65.0%) | 0.64 |
| Antepartum antibiotics, n (%)1 | 14 (82.4%) | 16 (84.2%) | 30 (83.3%) | 0.88 |
| Postpartum antibiotics, n (%) | 18 (100%) | 18 (81.8%) | 36 (90.0%) | 0.06 |
| Current antibiotics, n (%) | 8 (44.4%) | 4 (18.2%) | 12 (30.0%) | 0.07 |
| Age in days at first swab, mean ± SD | 19.6 ± 13.4 | 20.2 ± 18.8 | 19.9 ± 16.4 | 0.90 |
| Baseline arm GP bacterial count, mean log CFU/ml (range) | 2.39 (1.30–5.86) |
2.03 (0–3.48) |
2.19 (0–5.86) |
0.29 |
| Baseline groin GP bacterial count, mean log CFU/ml (range | 1.69 (0–5.18) |
1.91 (0–5.17) |
1.81 (0–5.18) |
0.65 |
Notes. 1Antepartum antibiotics data are available for 17/18 CHG-exposed and 19/22 non-exposed neonates. Abbreviations: CHG = chlorhexidine gluconate; GP = Gram-positive; CFU = colony forming units.