Table 1:
Patient Characteristics at Study Entry
| Variable | Category | CT | FLAM | S-MEC | Total |
|---|---|---|---|---|---|
| Total | 35 | 36 | 19 | 90 | |
| Age | Median (Q1,Q3) | 55 (48,62) | 62 (52,67) | 55 (42,63) | 57 (48,64) |
| Gender | Male | 21(60%) | 22(61%) | 11(58%) | 54(60%) |
| Female | 14(40%) | 14(39%) | 8(42%) | 36(40%) | |
| Race | White | 33(94%) | 30(86%) | 13(72%) | 76(86%) |
| Black | 1(3%) | 4(11%) | 2(11) | 7(8%) | |
| Asian | 1(3%) | 1(3%) | 2(11%) | 4(5%) | |
| Multi-race | 0(0.0) | 0(0.0) | 1(6%) | 1(1%) | |
| Unknown/Missing | 0 | 1 | 1 | 2 | |
| Disease Status | < 6 mos after 1st CR |
9(26%) | 11(31%) | 6(33%) | 26(29%) |
| 6–12 mos after 1st CR |
8(23%) | 8(22%) | 3(17%) | 19(21%) | |
| Refractory | 18(51%) | 17(47%) | 9(50%) | 44(49%) | |
| Unknown/Missing | 0 | 0 | 1 | 1 | |
| ECOG Performance | 0 | 10(29%) | 11(31%) | 4(22%) | 25(28%) |
| Status | 1 | 19(54%) | 21(58%) | 12(67%) | 52(58%) |
| 2 | 6(17%) | 4(11%) | 2(11%) | 12(13%) | |
| Unknown/Missing | 0 | 0 | 1 | 1 | |
| Leukemia | FAB M1 | 3(9%) | 6(17%) | 3(17%) | 12(13%) |
| Classification | FAB M2 | 8(23%) | 2(6%) | 2(11%) | 12(13%) |
| FAB M4 | 2(6%) | 4(11%) | 3(17%) | 9(10%) | |
| FAB M5 | 4(11%) | 3(8%) | 0 | 7(8%) | |
| FAB M6 | 1(3%) | 2(6%) | 0 | 3(3%) | |
| FAB M0 | 2(6%) | 0 | 0 | 2(2%) | |
| Acute myeloid leukemia with multilineage dysplasia |
0 | 3(8%) | 2(11%) | 5(6%) | |
| Therapy-related acute myeloid leukemia, NOS |
1(3%) | 2(6%) | 0 | 3(3%) | |
| Acute myeloid leukemia, NOS |
14(40%) | 14(39%) | 8(44%) | 36(40%) | |
| Unknown/Missing | 0 | 0 | 1 | 1 | |
| Marrow Blast (%) | Median (Q1,Q3) | 58.0 (21.0,80.0) | 48.0 (21.0,66.5) | 40.0 (29.0,79.0) | 49.0 (22.0,78.5) |
| [Min, Max] | [10.0,95.0] | [6.0,97.0] | [15.0,95.0] | [6.0,97.0] | |
| Unknown/Missing | 1 | 1 | 2 | 4 | |
| WBC (× 103/mm3) | Median (Q1,Q3) | 5 (2,8) | 2 (1,5) | 3 (2,4) | 3 (2,6) |
| [Min, Max] | [0,119] | [0,134] | [0,73] | [0,134] | |
| Granulocytes | Median (Q1,Q3) | 1371 (312,2642) | 684 (210,2140) | 728 (265,1375) | 850 (210,2370) |
| (AGC/ANC) | [Min, Max] | [0,35070] | [0,17750] | [0,4900] | [0,35070] |
| Unknown/Missing | 3 | 2 | 0 | 5 | |
| Platelet (× 103/mm3) | Median (Q1,Q3) | 42 (22,79) | 32 (18,65) | 65 (26,175) | 42 (21,85) |
| [Min, Max] | [11,206] | [6,252] | [8,310] | [6,310] | |
| Hemoglobin (g/dl) | Median (Q1,Q3) | 10 (8,11) | 10 (9,10) | 10 (9,11) | 10 (9,11) |
| [Min, Max] | [7,15] | [8,15] | [8,13] | [7,15] | |