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. 2018 Dec 14;10:1869–1877. doi: 10.2147/CLEP.S179555

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© 2018 Dennis et al. This work is published by Dove Medical Press Limited, and licensed under a Creative Commons Attribution License

The full terms of this license are available at https://creativecommons.org/licenses/by/4.0/. The license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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HRs for the association between HbA1c response and the risk of a drug-specific side effect (models 1–3).

Notes: HRs (95% CI) represent the increase in the risk of side effect for a 1% greater absolute HbA1c response. A HR of greater than 1 indicates an increased risk of side effect with greater HbA1c response.

Abbreviations: JMcum, joint model cumulative HbA1c; JMcv, joint model current value; LOCF, last observation carried forward; MFN, metformin; SU, sulfonylurea; TZD, thiazolidinedione.