Fig. 6.

Effect of intraperitoneal injection of αβ-meATP or PMA on 2-Hz EA analgesia in PDN rats as revealed by paw withdrawal threshold (PWT). EA treatment was administered once every day for 7 consecutive days after establishment of PDN model. Rats in the PDN + EA + αβ-meATP group and the PDN + EA + PMA group were hypodermically injected with αβ-meATP (0.6 μmol/l, 100 μl) and PMA (0.2 ng/μl, 100 μl) into the ventral surface of hind paws 10 min prior to EA treatment respectively. Rats in the PDN + EA + PBS group received the same dose of PBS buffer as a control. Data were presented as mean ± SD, n = 8 per group. ^△△ P < 0.01, compared with the PDN + EA + PBS group