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. 2018 Dec 18;8:17934. doi: 10.1038/s41598-018-36439-4

Table 6.

Effect of different metabolic precursors on the production of γ-PGA.

Strain Metabolic precursor γ-PGA (g/L) Remarks Reference
B. licheniformis ATCC 9945 Glutamic acid, citric acid 23.00 Utilized citrate rapidly at pH 6.5 which translated in to increased PGA production. 27
B. subtilis R 23 Glutamic acid, citric acid (Fed batch) 35.00 Pulsed-feeding of citric acid (1.44 g/L/h) and L-glutamic acid (2.4 g/L/h) when citric acid was depleted. 28
Glutamic acid, citric acid, α-ketoglutaric acid 25.38 Addition of α-ketoglutaric acid to the medium increased yield as well as molecular of PGA. 29
B. licheniformis NCIM 2324 Glutamic acid, citric acid, α-ketoglutaric acid, glutamine 35.75 Addition of α-ketoglutaric acid and glutamine to the medium increased yield as well as molecular of PGA. 30
B. subtilis Z15 CEGA, aspartic acid, phenylalanine 42.92 Crude extract of glutamic acid after isoelectric crystallization (CEGA) could be a replacement for glutamate for γ-PGA production. This study