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. 2018 Dec 12;11:456. doi: 10.3389/fnmol.2018.00456

Figure 3.

Figure 3

The effect of pretreatment with glutamate system modulator on hyperforin activity in the NOR in mice. (A,B) Hyperforin (2.5, 5, 10 mg/kg; i.p.) was administered 60 min before the first session. MK-801 (0.3 mg/kg; i.p.) was administered 30 min before the first training session of the NOR test. ###p < 0.001 vs. control, ***p < 0.001 vs. MK-801, n = 6–8; [A: F(4, 32) = 70.04; p = 0.0001], [B: F(4, 30) = 36.08; p = 0.0001]. All data was analyzed by one-way ANOVA and Newman-Keuls multiple comparisons test. All values are expressed as mean ± S.E.M.