Table 3.
Prevalence of Movement Disorders | Medication | NbN Classification |
---|---|---|
High | Haloperidol Chlorpromazine L-sulpiride |
D2 receptor antagonist D2 and 5-HT2 receptor antagonist D2 receptor antagonist |
Moderate-to-high | Ziprasidone Aripiprazole Risperidone Amisulpride |
D2 and 5-HT2 receptor antagonist D2 and 5-HT1A partial agonist and 5-HT2A receptor antagonist D2, 5HT2A and NE-alpha 2 receptor antagonist D2 receptor antagonist |
Moderate-to-low | Olanzapine Paliperidone Asenapine |
D2 and 5-HT2A receptor antagonist D2, 5HT2A and NE-alpha 2 receptor antagonist D2, 5HT2A and NE-alpha 2 receptor antagonist |
Low | Clozapine Quetiapine |
D2, 5HT2A and NE-alpha 2 receptor antagonist D2 and 5HT2A receptor antagonist – norepinephrine transporter inhibitor |
The table indicates also their classification based on Principal Mode of Action, according to the neuroscience-based nomenclature (NbN).