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. 2018 Oct 4;27(11):1603–1612. doi: 10.1177/0963689718802754

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig 1. — Transplantation of hWJ-MSCs reduced brain infarction and behavioral deficits in stroke rats. (A) Timeline of the experiment. (B) Averaged infarct volume, measured by T2WI on day 4, was significantly reduced by the hWJ-MSC graft (p = 0.0194). (C) Representative T2WIs. The size of the lesion was reduced in an animal grafted with hWJ-MSCs, as compared with another animal treated with vehicle. (D) Bederson’s neurological and body asymmetry tests were carried out on days 3 and 5 after treatment. Transplantation with hWJ-MSCs significantly reduced the Bederson’s score (p < 0.001) and body asymmetry (p < 0.001, two-way ANOVA).

ANOVA: analysis of variance; hWJ-MSC: Wharton’s jelly-derived mesenchymal stromal cell; T2WI: T2-weighted image.