TABLE 3.

Structure-activity relationships for DG167 analogs^a

^acl_int, intrinsic clearance; nd, not done; Me, methyl; Et, ethyl; Bu, butyl; Pr, propyl; Pen, pentyl; Hex, hexyl; Bn, benzyl; MeO, methoxy.

^bData corresponding to MLM t_1/2 (in minutes) without NADPH are shown in parentheses.