Fig. 2.

Human cytomegalovirus induced EC IL-11 and IL-6 expression is differentially modulated by viral gene expression. EC were mock- or hCMV-inoculated and treated with or without ganciclovir (GCV) at the concentrations stated. Supernatants were collected over a 24 h period at 1, 4 or 7 days post inoculation (dpi), and secreted (A) IL-11 or (B) IL-6 protein was measured by ELISA. EC were harvested at 7dpi and analysed for mRNA expression of (C) IL-11 or (D) IL-6. GCV: Ganciclovir. Data are means ± SEM of 3–6 experiments (all using EC from independent donors) ^*p < 0.05 ^**p < 0.01 ^***p < 0.001.