Table II.
Baseline characteristics of the 5713 participants enrolled in TIPS-3
| Variable | |
|---|---|
| Mean age, years (SD) | 63.9 (6.6) |
| Female, N (%) | 3026 (53.0%) |
| Country of recruitment, N (%) | |
| India | 2739 (47.9)⁎ |
| Philippines | 1676 (29.3) |
| Colombia | 489 (8.6) |
| Bangladesh | 295 (5.2) |
| Canada | 131 (2.3) |
| Malaysia | 119 (2.1) |
| Indonesia | 118 (2.1) |
| Tunisia | 107 (1.9) |
| Tanzania | 39 (0.7)⁎ |
| Risk factors: | |
| Self-reported hypertension, N (%) | 4436 (77.6) |
| Self-reported diabetes, N (%) | 1841 (32.2) |
| Fasting glucose ≥6.1 mmol/L (%) | 1961 (34.3) |
| Current smoker, N (%) | 512 (9) |
| Mean INTERHEART Risk Score | 16.8 (4.6) |
| Physiologic parameters: | |
| Mean heart rate, beats per minute (SD) | 77.0 (10.6) |
| Mean systolic blood pressure, mmHg (SD) | 144.5(16.8) |
| Mean diastolic blood pressure, mmHg (SD) | 83.9(9.7) |
| Mean total cholesterol, mmol/L (SD) | 5.1 (1.2) |
| Mean low density lipoprotein, mmol/L (SD) | 3.1 (1.1) |
| Mean high density lipoprotein, mmol/L (SD) | 1.2 (0.3) |
| Mean triglycerides, mmol/L (SD) | 1.6 (0.8) |
| Mean fasting plasma glucose, mmol/L (SD) | 6.3 (2.5) |
| Mean Creatinine, mmol/L (SD) | 81.5 (23.3) |
| Mean BMI, kg/m2 (SD) | 25.8 (4.8) |
| Mean waist-to-hip ratio (SD) | |
| Males | 0.96 (0.06) |
| Females | 0.91 (0.07) |
⁎
After randomization, all patients from Tanzania (n = 39) and a small number in India (N = 18) were withdrawn because of regulatory barriers resulting in site closures. Participants at these sites were censored at the time of the site closure. Currently 5656 participants are actively in follow-up.