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. 2018 Nov 11;9(24):4578–4585. doi: 10.7150/jca.28040

Figure 3.

Figure 3

Knockout of MTF1 led to reduced cell proliferation, migration, and invasion in ovarian cancer cells. A, B. Cell proliferation in MTF1 KO and control SKOV3 (A) and OVCAR3 (B) cells at different time points determined by MTT assay. C, D. Cell survival in MTF1 KO SKOV3 (C) and OVCAR3 (D) cells determined by colony formation assay. E, F. Cell migration in MTF1 KO and control SKOV3 (E) and OVCAR3 (F) cells determined using transwell plates. G, H. Cell invasion in MTF1 KO and control SKOV3 (G) and OVCAR3 (H) cells examined using Matrigel-coated plates. *p < 0.05; **p < 0.01;***p < 0.001