Table 2.
The relationship between CLDN10 and clinicopathologic characteristics in TCGA cohort.
| Clinicopathologic characteristics | Low expression (%) | High expression (%) | X2 | P |
|---|---|---|---|---|
| Age | 6.269 | 0.012* | ||
| ≤45 | 104(41.4) | 132(52.6) | ||
| >45 | 147(58.6) | 119(47.4) | ||
| Gender | 0.01 | 0.92 | ||
| Female | 184(73.3) | 183(72.9) | ||
| Male | 67(26.7) | 68(27.1) | ||
| Histological type | 91.03 | 0.000* | ||
| Classical | 148(59.0) | 208(83.2) | ||
| Follicular | 92(36.7) | 9(3.6) | ||
| Tall Cell | 7(2.8) | 28(11.2) | ||
| other | 4(1.6) | 5(2.0) | ||
| Tumor size | 1.653 | 0.199 | ||
| ≤20mm | 78(31.1) | 65(25.9) | ||
| >20mm | 173(68.9) | 186(74.1) | ||
| T stage | 1.653 | 0.199 | ||
| T1 | 78(31.1) | 65(25.9) | ||
| >T1 | 173(68.9) | 186(74.1) | ||
| Extrathyroidal invasion | 0.113 | 0.737 | ||
| YES | 5(2) | 4(1.6) | ||
| NO | 246(98) | 247(98.4) | ||
| Lymph node metastasis | 52.938 | 0.000* | ||
| YES | 71(28.3) | 152(60.6) | ||
| NO | 180(71.7) | 99(39.4) | ||
| AJCC | 1.079 | 0.299 | ||
| I+II | 172(68.5) | 161(64.1) | ||
| III+IV | 79(31.5) | 90(35.9) | ||
* P-value < 0.05