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. 2018 Nov 22;15(14):1731–1736. doi: 10.7150/ijms.27901

Table 3.

Distribution frequency of the clinical status and HMGB1 rs1045411 genotype frequencies in 159 female patients with UCC.

HMGB1 (rs1045411)
Variable CC (%) (n=103) CT+TT (%) (n=56) OR (95% CI) p value
Stage
Non muscle invasive tumor (pTa-pT1) 50 (48.5%) 34 (60.7%) 1.00
Muscle invasive tumor (pT2-pT4) 53 (51.5%) 22 (39.3%) 0.610 (0.315-1.182) p=0.142
Tumor T status
Ta 12 (11.7%) 14 (25.0%) 1.00
T1-T4 91 (88.3%) 42 (75.0%) 0.396 (0.169-0.929) p=0.030*
Lymph node status
N0 92 (89.3%) 49 (87.5%) 1.00
N1+N2 11 (10.7%) 7 (12.5%) 1.195 (0.436-3.277) p=0.729
Metastasis
M0 102 (99.0%) 54 (96.4%) 1.00
M1 1 (1.0%) 2 (3.6%) 3.778 (0.335-42.613) p=0.250
Histopathologic grading
Low grade 9 (8.7%) 5 (8.9%) 1.00
High grade 94 (91.3%) 51 (91.1%) 0.977 (0.311-3.069) p=0.968

Note: * and Bold text indicated a significant association with p value <0.05.