Table 3.
HMGB1 (rs1045411) | ||||
---|---|---|---|---|
Variable | CC (%) (n=103) | CT+TT (%) (n=56) | OR (95% CI) | p value |
Stage | ||||
Non muscle invasive tumor (pTa-pT1) | 50 (48.5%) | 34 (60.7%) | 1.00 | |
Muscle invasive tumor (pT2-pT4) | 53 (51.5%) | 22 (39.3%) | 0.610 (0.315-1.182) | p=0.142 |
Tumor T status | ||||
Ta | 12 (11.7%) | 14 (25.0%) | 1.00 | |
T1-T4 | 91 (88.3%) | 42 (75.0%) | 0.396 (0.169-0.929) | p=0.030* |
Lymph node status | ||||
N0 | 92 (89.3%) | 49 (87.5%) | 1.00 | |
N1+N2 | 11 (10.7%) | 7 (12.5%) | 1.195 (0.436-3.277) | p=0.729 |
Metastasis | ||||
M0 | 102 (99.0%) | 54 (96.4%) | 1.00 | |
M1 | 1 (1.0%) | 2 (3.6%) | 3.778 (0.335-42.613) | p=0.250 |
Histopathologic grading | ||||
Low grade | 9 (8.7%) | 5 (8.9%) | 1.00 | |
High grade | 94 (91.3%) | 51 (91.1%) | 0.977 (0.311-3.069) | p=0.968 |
Note: * and Bold text indicated a significant association with p value <0.05.