Table 4.

Distribution frequency of the clinical status and HMGB1 rs1045411 genotype frequencies in 300 UCC patients with non-smoker.

	HMGB1 (rs1045411)
Variable	CC (%) (n=194)	CT+TT (%) (n=106)	OR (95% CI)	p value
Stage
Non muscle invasive tumor (pTa-pT1)	99 (51.0%)	67 (63.2%)	1.00
Muscle invasive tumor (pT2-pT4)	95 (49.0%)	39 (36.8%)	0.607 (0.374-0.985)	p=0.043*
Tumor T status
Ta	34 (17.5%)	27 (25.5%)	1.00
T1-T4	160 (82.5%)	79 (74.5%)	0.622 (0.351-1.102)	p=0.102
Lymph node status
N0	174 (89.7%)	94 (88.7%)	1.00
N1+N2	20 (10.3%)	12 (11.3%)	1.111 (0.520-2.371)	p=0.786
Metastasis
M0	191 (98.5%)	104 (98.1%)	1.00
M1	3 (1.5%)	2 (1.9%)	1.224 (0.201-7.445)	p=0.826
Histopathologic grading
Low grade	23 (11.9%)	13 (12.3%)	1.00
High grade	171 (88.1%)	93 (87.7%)	0.962 (0.466-1.988)	p=0.917

Note: * and Bold text indicated a significant association with p value <0.05.