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. 2018 Oct 20;15(14):1591–1599. doi: 10.7150/ijms.27953

Figure 1.

Figure 1

Schematic Representation of Molecular Alterations in Hepatocytes in the pathogenesis of NAFLD. Diet-induced metabolic complications and systemic ROS causes the molecular alterations in hepatocytes, subsequently activating macrophages and releasing pro-inflammatory cytokines. This pathogenesis potentially plays a crucial role in the disease progression to NAFLD.