Table 1.

Clinical characteristics and correlations with mRNA expression of AURKA, TPX2 and CDC20.

Characteristic	n=497	AURKA			TPX2			CDC20
		Lown=248	Highn=249	P value	Lown=248	Highn=249	P value	Lown=248	Highn=249	P value
Age (years)				0.043			0.029			<0.001
<65	214	96	118		96	118		86	128
>=65	264	143	121		145	119		156	108
Not given	19	9	10		7	12		6	13
Gender				<0.001			0.005			0.005
Female	230	95	135		99	131		99	131
Male	267	153	114		149	118		149	118
Smoking history				0.002			0.008			0.004
Smoker	422	198	224		200	222		199	223
Non-smoker	75	50	25		48	27		49	26
New tumor event				0.114			0.008			0.013
YES	118	53	65		47	71		48	70
NO	257	138	119		140	117		140	117
Not given	122	57	65		61	61		60	62
Pathological T stage				0.062			0.001			0.001
T1	164	94	70		102	64		100	64
T2	267	122	145		115	152		115	152
T3 + T4	64	31	33		30	34		32	32
unknown	2	1	1		1	1		1	1
Therapy outcome				0.002			<0.001			0.014
*CR+PR	232	128	104		131	101		127	105
*SD+PD	71	24	47		23	48		27	44
unknown	194	96	98		94	100		94	100

*CR+PR:Complete Remission+Partial Remission.

*SD+PD:Stable Disease+Progressive Disease.