Table 3.

Characteristics of patients with acute ischemic stroke stratified by the median of TIPE2.

Characteristic	TIPE2 mRNA<4.75(n=91)	TIPE2 mRNA >=4.75(n=91)	P-value
Sex			0.767
Female	45 (49.45%)	47 (51.65%)
Male	46 (50.55%)	44 (48.35%)
Age,Years	69.00 (61.50-76.00)	66.00 (56.50-75.00)	0.293
BMI,kg/m2	27.90 (26.00-29.00)	27.00 (25.00-29.05)	0.366
Time Onset,hours			0.018
<6	5 (5.49%)	3 (3.30%)
>=6, <12	36 (39.56%)	22 (24.18%)
>=12, <18	21 (23.08%)	24 (26.37%)
>=18, <24	22 (24.18%)	20 (21.98%)
>=24	7 (7.69%)	22 (24.18%)
Lesion volumes,mL	1.50 (0.34-20.25)	0.50 (0.10- 1.90)	0.012
Lesion volumes classification			0.318
Large	16 (17.58%)	9 ( 9.89%)
Middle	4 ( 4.40%)	4 ( 4.40%)
Small	71 (78.02%)	78 (85.71%)
Before and after cycle			0.111
LACS	1 ( 1.10%)	5 ( 5.49%)
POCS	20 (21.98%)	28 (30.77%)
TACS	62 (68.13%)	48 (52.75%)
PACS	8 ( 8.79%)	10 (10.99%)
NIHSS	5.00 (2.50-11.50)	3.00 (2.00- 7.00)	0.008
HSCRP,mg/dL	7.10 (5.15-12.40)	6.20 (4.60- 8.40)	0.075
GFR,mL/min/1.73m2	87.00 (76.00- 99.25)	0.50 (78.00-103.00)	0.607
FBG,mmol/L	5.70 (4.90-7.50)	5.60 (5.10-7.00)	0.424
TG,mmol/L	1.60 (0.97-2.10)	1.23 (0.90-1.95)	0.115
TC,mmol/L	4.60 (3.90-5.42)	4.61 (3.97-5.45)	0.743
LDL,mmol/L	3.00 (2.54-3.73)	3.10 (2.60-3.65)	0.535
HCY,umol/L	11.80 (9.60-15.30)	11.90 (9.80-14.60)	0.475
TNF-α	4.95 (3.68-7.46)	2.64 (1.18-3.85)	<0.001
AP-1	4.86 (3.78-6.92)	3.85 (1.92-5.42)	<0.001
IFN-γ	4.86 (3.75-6.90)	3.21 (1.86-5.29)	<0.001
IL-1β	4.67 (3.03-7.08)	4.38 (2.79-5.71)	0.167
IL6	3.89 (2.64-6.00)	4.30 (2.56-8.59)	0.073
IL10	2.48 (1.52-4.24)	5.09 (2.59-8.50)	<0.001
NF-κB	3.60 (2.57-5.16)	2.18 (1.05-3.11)	<0.001
Outcome			<0.001
Survival	62 (68.13%)	87 (95.60%)
Nonsurvival	29 (31.87%)	4 (4.40%)