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Hypoxia-activated 3D photoacoustic PA imaging of tumors in vivo after intravenous injection of 200 μL 40 μg/mL IR1048-MZ. The impulse excitation wavelength was 880 nm. (A) PA imaging of tumors in living mice at different time intervals and (B) quantified PA intensities. (C) Penetration depth of PA imaging in the longitudinal section (L) 14 h post-injection.
