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. 2018 Nov 12;8(21):5828–5841. doi: 10.7150/thno.26706

Figure 1.

Figure 1

Remote loading of the amino diatrizoic acid (ADA) imaging agent (A) into liposomes by transmembrane pH gradients. Possible iodine labels for SPECT, therapy, PET and CT are outlined. Equilibria governing the remote loading of amine-functionalized compounds into liposomes via ammonium sulfate-based (B) or citrate-based (C) pH gradients are shown.