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. 2018 Dec 19;8:17970. doi: 10.1038/s41598-018-36231-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Overview of the lncRNA expression and significantly differentially expressed lncRNAs between the parental and docetaxel-resistant cell groups. (A) The subgroups and number of lncRNAs detected in the docetaxel-resistant and parental cell lines (P represents the parental cell line; T represents the docetaxel-resistant cell line). (B) Volcano figure showing the significantly differentially expressed lncRNAs in the MDA-RES and MCF7-RES cells compared to their parental cells. The blue dots represent lncRNAs with |Log2FC| > 1, FDR < 0.1. (C) Upper panel: Venn diagrams of consistently up-regulated or down-regulated lncRNAs in both of the MDA-RES and MCF7-RES cells. Lower panel: the bar chat shows the subgroups and numbers of significantly up-regulated or down-regulated lncRNAs. (D) Complete-linkage clustering with the 72 consistent SDE lncRNAs in the 12 samples.