Table 1.

Summary of data yield and quality control.

Sample	MCF7_12_P	MCF7_14_P	MCF7_15_P	MCF7_13_T	MCF7_14_T	MCF7_15_T	MDA_13_P	MDA_14_P	MDA_16_P	MDA_14_T	MDA_15_T	MDA_16_T
Number of raw reads	155,368,324	150,086,362	154,603,830	151,890,702	146,565,380	150,531,888	154,601,446	150,960,982	155,560,554	150,067,038	154,602,638	151,145,840
Raw data size(Gb)	13.98	13.51	13.91	13.67	13.19	13.55	13.91	13.59	14.00	13.51	13.91	13.60
Number of clean reads	147,254,586	145,503,292	148,444,124	145,691,082	141,393,020	143,013,044	149,175,500	146,265,718	146,883,552	144,846,612	149,085,610	142,568,132
Clean data size(Gb)	13.25	13.10	13.36	13.11	12.73	12.87	13.43	13.16	13.22	13.04	13.42	12.83
Clean data/Raw data(%)	94.78	96.95	96.02	95.92	96.47	95.01	96.49	96.89	94.42	96.52	96.43	94.32
Q30 reads(%)	88.66	92.75	89.63	89.73	92.72	88.81	90.36	92.57	89.23	92.96	90.54	88.38
GC(%)	49.87	47.26	49.83	49.46	47.33	49.89	47.54	46.84	47.42	46.58	48.24	49.61
Reads mapped to genome	126,241,357	129,177,823	134,000,511	133,059,665	125,613,559	122,233,249	133,556,825	129,562,173	126,202,348	128,884,515	132,119,668	118,246,009
Mapping rate(%)	85.73	88.78	90.27	91.33	88.84	85.47	89.53	88.58	85.92	88.98	88.62	82.94

For the sample names, P represents the parental cells, T represents the docetaxel-resistant cells, number represents the passage.