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. 2018 Dec 18;16:366. doi: 10.1186/s12967-018-1740-z

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Dysregulation of AZIN1 RNA editing and ADAR1 expression status in tissues from GC patients. a AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) were significantly increased in primary cancer tissues compared with adjacent normal mucosa. b ROC curve analysis for AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) for distinguishing between GC and normal gastric mucosa. AZIN1 RNA editing levels and ADAR1 expression levels could distinguish GC tissues from normal gastric mucosa with area under the curve values of 0.75 (95% CI 0.69–0.8), 0.66 (95% CI 0.6–0.84), respectively. c Scattergrams of AZIN1 RNA editing levels (left) and ADAR1 expression levels (right) according to UICC classification in gastric cancer patients