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. 2018 Dec 18;16:366. doi: 10.1186/s12967-018-1740-z

Table 1.

Correlation between clinicopathological Variables and AZIN1 RNA editing and ADAR1 expression in Gastric Cancer patients

Variable n AZIN1 RNA editing P value ADAR1 expression P value
High (n = 56) Low (n = 84) High (n = 78) Low (n = 62)
Gender
 Male 110 44 66 1 62 48 0.77
 Female 30 12 18 16 14
Age (year)
 69≥a 72 31 41 0.45 42 30 0.52
 >69 68 25 43 36 32
Histological type
 Intestinal type 69 29 40 0.63 41 28 0.39
 Diffuse type 71 27 44 37 34
Pathological T category
 pT1/2 50 14 36 0.031* 24 26 0.17
 pT3/4 90 42 48 54 36
Vessel invasion
 Present 111 43 68 0.55 62 49 0.95
 Absent 29 13 16 16 13
Lymphovascular invasion
 Present 128 52 76 0.62 74 54 0.1
 Absent 12 4 8 4 8
Lymph node metastasis
 N0 43 11 32 0.021* 18 25 0.029*
 N1 97 45 52 60 37
Peritoneal metastasis
 P0 117 43 74 0.08 61 56 0.06
 P1 23 13 10 17 6
Distant metastasis
 M0 101 39 62 0.59 49 52 0.006*
 M1 39 17 22 29 10
UICC TNM classification
 Stage I 23 5 18 0.028* 11 12 0.004*
 Stage II 39 12 27 15 24
 Stage III 39 22 17 23 16
 Stage IV 39 17 22 29 10

* P < 0.05

aThe median age at surgery is 69 years in this cohort