Table 3.
Overall results regarding HLA-DQB1 polymorphisms in hepatitis B virus-susceptible patients
| HLA-DQB1* | N | Heterogeneity | Overall relationship | |||
|---|---|---|---|---|---|---|
| I2 (%) | P | Model | OR (95% CI) | P | ||
| 02:01 | 5 | 0 | 0.43 | F | 0.96 (0.74–0.23) | 0.74 |
| 03:01 | 6 | 63 | 0.02 | R | 1.06 (0.87–1.28) | 0.58 |
| 03:02 | 6 | 66 | 0.03 | R | 0.83 (0.64–1.07) | 0.16 |
| 03:03 | 6 | 78 | 0.0004 | R | 1.20 (0.95–1.52) | 0.13 |
| 04:01 | 5 | 82 | 0.0001 | R | 1.33 (1.02–1.73) | 0.03 |
| 04:02 | 6 | 41 | 0.13 | F | 0.89 (0.78–1.02) | 0.09 |
| 05:01 | 6 | 46 | 0.10 | F | 0.59 (0.51–0.69) | < 0.00001 |
| 05:02 | 6 | 0 | 0.55 | F | 1.22 (1.04–1.42) | 0.01 |
| 05:03 | 6 | 0 | 0.76 | F | 1.16 (1.02–1.31) | 0.02 |
| 06:01 | 5 | 83 | < 0.00001 | R | 1.32 (1.02–1.70) | 0.03 |
| 06:02 | 6 | 91 | < 0.00001 | R | 1.13 (0.66–1.96) | 0.65 |
| 06:03 | 5 | 67 | 0.02 | R | 0.28 (0.08–1.00) | 0.05 |
| 06:04 | 5 | 64 | 0.03 | R | 0.31 (0.20–0.49) | < 0.00001 |
OR odds ratio, CI confidence interval, F fix effects model, R random effects model
Italic values indicate significance of p value (p≤0.05)