Table 4.
Meta-analysis of HLA-DQB1 polymorphisms and hepatitis B virus clearance
| First author | Year | Ethnicity | Total | Genotyping method | Refs | |
|---|---|---|---|---|---|---|
| Spontaneous clearance | Chronic HBV infections | |||||
| Zhang | 2015 | Chinese (Uygur) | 80 | 110 | PCR-SSP | [18] |
| Cho | 2008 | Koreans | 80 | 384 | PCR-SBT | [24] |
| Liu | 2007 | Chinese (Han) | 100 | 168 | PCR-SSP | [25] |
| Zhu | 2007 | Chinese (Han) | 133 | 151 | PCR-SSP | [20] |
| Jiang | 2003 | Chinese (Han) | 30 | 52 | PCR-SSP | [28] |
| Thio | 1999 | African American | 60 | 31 | PCR-SSP | [29] |
| Chen | 1996 | Caucasian | 119 | 58 | PCR-SSO | [23] |
HBV hepatitis B virus, Refs references, PCR polymerase chain reaction, SSP single specific primer, SBT sequenced-based typing, SSO sequence-specific oligonucleotide