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. 2018 Dec 18;18:194. doi: 10.1186/s12890-018-0758-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Variation of histogram characteristics according to lung disease severity. Histogram of lung densities in a patient with mild disease (black line; FEV₁ = 81%; FVC = 101%;SD = 110.1; kurtosis =31.4). The histogram of lung densities in a patient with severe disease (grey line; FEV₁ = 25%; FVC = 54%) demonstrates higher scattering (SD = 213.9) and flattening (kurtosis = 6.7) of the curve