Table 2.
The difference in average axon diameter, midsagittal area, and myelin thickness in five CC segments in autistic (A) and control (C) subjects
Parameter | Group | CC Segment | ||||
---|---|---|---|---|---|---|
S I | S II | S III | S IV | S V | ||
Axon diameter (μm) (SE) | C | 0.869 (0.025) | 0.945 (0.026) | 1.108 (0.036) | 1.120 (0.058) | 1.075 (0.043) |
A | 0.772 (0.016) | 0.836 (0.020) | 0.837 (0.059) | 0.858 (0.061) | 0.768 (0.046) | |
p < | 0.005** | 0.004** | 0.001*** | 0.010** | 0.0002*** | |
Difference | −11.2% | −11.5% | −24.4% | −23.4% | −28.6% | |
Axon area (μm2) (SE) | C | 0.613 (0.042) | 0.739 (0.039) | 1.075 (0.068) | 1.157 (0.117) | 0.968 (0.086) |
A | 0.462 (0.024) | 0.543 (0.032) | 0.594 (0.071) | 0.620 (0.081) | 0.469 (0.056) | |
p < | 0.006** | 0.001*** | 0.0002*** | 0.005** | 0.0002*** | |
Difference | −24.6% | −26.5% | −44.8% | −46.9% | −51.6% | |
Myelin thickness (μm) (SE) | C | 0.149 (0.006) | 0.153 (0.006) | 0.162 (0.005) | 0.163 (0.008) | 0.157 (0.004) |
A | 0.139 (0.003) | 0.149 (0.003) | 0.142 (0.011) | 0.145 (0.007) | 0.132 (0.008) | |
p < | 0.197 | 0.538 | 0.092 | 0.141 | 0.018* | |
Difference | ns | ns | ns | ns | −15.8% |
CC Corpus callosum, SE standard error, ns not significant
*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001