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. 2018 Dec 18;16:365. doi: 10.1186/s12967-018-1742-x

Table 1.

The clinicopathological characteristics of patients in the training, validation and combined cohorts

Clinical and pathological indexes Training cohort Validation cohort P Combined cohort
N = 138 (%) N = 171 (%) N = 309 (%)
Age (y)
 ≤ 60 47 (34.06) 65 (38.01) 0.472 112 (36.25)
 > 60 91 (65.94) 106 (61.99) 197 (63.75)
Gender
 Male 81 (58.70) 90 (52.63) 0.286 171 (55.34)
 Female 57 (41.30) 81 (47.37) 138 (44.66)
Smoking
 No 89 (64.49) 133 (77.78) 0.010 222 (71.84)
 Yes 49 (35.51) 38 (22.22) 87 (28.16)
Alcohol use
 No 104 (75.36) 141 (82.46) 0.126 245 (79.29)
 Yes 34 (24.64) 30 (17.54) 64 (20.71)
Tumor size
 T1–T2 103 (74.64) 135 (78.95) 0.371 238 (77.02)
 T3–T4 35 (25.36) 36 (21.05) 71 (22.98)
Pathological grade
 I 83 (60.14) 95 (55.56) 0.417 178 (57.61)
 II–III 55 (39.86) 76 (44.44) 131 (42.39)
Cervical nodal metastasis
 N0 112 (81.16) 121 (70.76) 0.035 233 (75.40)
 N+ 26 (18.84) 50 (29.24) 76 (24.60)
Clinical stage
 I–II 91 (65.94) 100 (58.48) 0.180 191 (61.81)
 III–IV 47 (34.06) 71 (41.52) 118 (38.19)
SII
 < 484.5 96 (69.57) 105 (61.40) 0.135 201 (65.05)
 ≥ 484.5 42 (30.43) 66 (38.60) 108 (34.95)
NLR
 < 2.9 109 (78.99) 129 (75.44) 0.461 238 (77.02)
 ≥ 2.9 29 (21.01) 42 (24.56) 71 (22.98)
PLR
 < 170.2 114 (82.61) 129 (75.44) 0.126 243 (78.64)
 ≥ 170.2 24 (17.39) 42 (24.56) 66 (21.36)
Median survival (months) 48 (4–134) 45 (4–138) 46 (4–138)

The italic values in the table denotes P-values less than 0.05 with statistical significance