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. 2018 Dec 18;19:40. doi: 10.1186/s12865-018-0281-9

Fig. 1.

Fig. 1

Mechanisms of oncolytic virus selective killing tumor cells. Local replication of oncolytic virus induces lysis of tumor cells results in release of tumor-derived antigens which promote the activity of the cancer-immunity cycle, resulting in the specific antitumor immunity in the course of its oncolytic activities that act on remote lesions, ultimately killing the tumor cells selectively