Figure 4.

Inhibition of the TGF‐β pathway restores the MCPIP1‐dependent cell migration. a) Comparison of the migration distances and percentage of high‐migratory versus low‐migratory cells (mean ± SD is shown in corresponding bar plots to represent the results) b) for MCF‐7/Vector, MDA‐MB‐231/Vector, MDA‐MB‐231/MCPIP1, and SB431542 (10 × 10⁻⁶ m) pretreated MDA‐MB‐231/Vector cells. c) Quantification of the lung weight and d) the number of nodules on lungs of BALB/c nude mice. Representative images of e) lungs and f) haematoxylin and eosin staining of lung sections from BALB/c nude mice, scale bars, 200 µm.