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Sketch of the system with inset showing the magnification at the 3D nanostructure tip. On top of the 3D nanostructures (yellow), cells (in orange) were tightly sealed to the substrate. The plasmonic modes of the 3D nanoelectrode were excited by a 785 nm laser, and the enhanced Raman signals coming from the molecules close to it were collected. The different colors of the substrate represent bulk quartz (salmon), gold nanoelectrode (yellow), and an SU8 passivation layer (green).
