Figure 2. Single and combined treatment of As2O3 and resveratrol induced alteration of nuclear morphology. SK-N-SH cells were untreated (A), or treated with 75 μg/ml resveratrol alone (B), 2 μM As2O3 alone (C) or As2O3 plus resveratrol (D) for 48 h. Chromatin condensation and nuclear fragmentation of SK-N-SH cells were observed using staining with 4’,6-diamidine-2-phenylindole and imaged under fluorescent microscopy. Representative images from triplicate experiments are shown.
