Table 4.
Changes of echocardiographic parameters after 3 months of placebo treatment
| Mean ± standard deviation | 95% CI (mean) | median and interquartile ranges | |||
|---|---|---|---|---|---|
| Parameter | N | lower limit | upper limit | ||
| Echocardiography | |||||
| right atrial area [cm2] | 5 | −0.4 ± 2.9 | −4.1 | 3.2 | 1 [−3.2; 2] |
| right ventricular area [cm2] | 5 | 2.0 ± 6.4 | −6.0 | 9.8 | 0 [−5.3; 10] |
| TAPSE [mm] | 5 | 0.5 ± 3.3 | −3.6 | 4.5 | 0 [−2.6; 6] |
| RV thickness [mm] | 4 | 1.0 ± 0.8 | −0.3 | 2.3 | 1.0 [0.5; 1.5] |
| TRV [cm/sec] | 4 | 0.1 ± 0.2 | −0.3 | 0.4 | 0.1 [−0.1; 0.3] |
| IVC diameter [mm] | 5 | −0.4 ± 2.7 | −3.8 | 2.9 | 0 [0; 0.8] |
| LV-EI | 5 | −0.1 ± 0.1 | −0.2 | 0.03 | −0.1 [− 0.2; 0] |
| PA diameter [mm] | 4 | −0.25 ± 1.3 | −2.3 | 1.8 | 0 [−1.0; 0.5] |
TAPSE = tricuspid annular plane systolic excursion; FAC = Fractional area change; RV = right ventricular
TRV tricuspid regurgitation velocity, IVC inferior vena cava, LV-EI left ventricular eccentricity index
PA pulmonary artery