Table 3.
Enriched GO terms in up and down-regulated genes
| Direction | Pathways | nGenes | adj.Pval |
|---|---|---|---|
| Down Regulated |
Cell cycle | 259 | 4.50E-46 |
| Cell cycle process | 207 | 1.70E-42 | |
| Mitotic cell cycle | 169 | 5.60E-38 | |
| Chromosome segregation | 92 | 2.80E-35 | |
| Mitotic cell cycle process | 145 | 2.00E-33 | |
| Sister chromatid segregation | 72 | 5.20E-33 | |
| Cell division | 118 | 5.20E-33 | |
| Nuclear chromosome segregation | 80 | 2.20E-30 | |
| Nuclear division | 86 | 5.60E-26 | |
| Organelle organization | 350 | 1.20E-24 | |
| Mitotic nuclear division | 65 | 3.50E-24 | |
| Organelle fission | 88 | 5.80E-24 | |
| Cytoskeleton organization | 159 | 1.70E-23 | |
| Cell cycle phase transition | 98 | 2.60E-21 | |
| Mitotic sister chromatid segregation | 45 | 4.00E-21 | |
| Up Regulated |
Cell surface receptor signaling pathway | 258 | 3.40E-25 |
| Regulation of cell proliferation | 171 | 8.20E-23 | |
| Cell proliferation | 195 | 7.40E-22 | |
| Regulation of signaling | 265 | 3.80E-21 | |
| Response to organic substance | 259 | 1.20E-20 | |
| Regulation of cell communication | 260 | 1.20E-20 | |
| Locomotion | 165 | 1.20E-19 | |
| Regulation of signal transduction | 239 | 1.30E-19 | |
| System development | 332 | 1.00E-18 | |
| Regulation of cellular component movement | 100 | 3.70E-17 | |
| Regulation of response to stimulus | 291 | 8.20E-17 | |
| Response to endogenous stimulus | 143 | 1.20E-16 | |
| Response to chemical | 319 | 1.70E-16 | |
| Cellular response to organic substance | 211 | 1.80E-16 | |
| Cell migration | 131 | 2.10E-16 |