Table 5.
TF motifs enriched in gene promoters (300 bp) of up- or down-regulated genes
| List | Motif | TF | TF family | FDR |
|---|---|---|---|---|
| Down Regulated |
GGCGGGAA | E2F4 | E2F | 3.40E-14 |
| GGCCGGAG | MBD2 | MBD | 7.70E-14 | |
| CACGTG | TCFL5 | bHLH | 2.30E-11 | |
| GGGGGCGGGGC | SP2 | C2H2 ZF | 3.40E-11 | |
| GGGCGGGAA | E2F6 | E2F | 8.60E-10 | |
| GTGGGCGTGGC | SP6 | C2H2 ZF | 2.10E-09 | |
| TGCGGG | ZBTB1 | C2H2 ZF | 2.20E-08 | |
| GGGCGTG | KLF7 | C2H2 ZF | 2.90E-08 | |
| ATGCGTGGGCGG | EGR4 | C2H2 ZF | 1.50E-07 | |
| CACAGCGGGGGGTC | ZIC4 | C2H2 ZF | 1.80E-07 | |
| Up Regulated |
GGGGGCGGGGC | SP2 | C2H2 ZF | 2.20E-06 |
| GGGGGGGGGCC | PATZ1 | C2H2 ZF | 2.40E-06 | |
| TGCGGG | ZBTB1 | C2H2 ZF | 2.60E-06 | |
| GGGGGGT | ZIC5 | C2H2 ZF | 1.40E-04 | |
| GGCCGGAG | MBD2 | MBD | 1.50E-04 | |
| CACGTG | TCFL5 | bHLH | 1.50E-04 | |
| CACAGCGGGGGGTC | ZIC4 | C2H2 ZF | 1.10E-03 | |
| GGGGCCCAAGGGGG | PLAG1 | C2H2 ZF | 1.10E-03 | |
| GTGGGCGTGG | SP8 | C2H2 ZF | 1.40E-03 | |
| GTGGGCGTGGC | SP6 | C2H2 ZF | 2.30E-03 |