Table 7.

Multiple regression analysis according to Cutolo’s patterns

	B	95% CI	p value
FVC as dependent variable
Male gender	−12.3	−21.0 to −3.5	0.006
Interstitial findings on HRCT	−13.5	−20.2 to −6.7	< 0.001
ACA positivity	8.6	−0.1 to 17.4	0.051
Cutolo’s late pattern	−14.3	−26.1 to −2.5	0.018
DLCO as dependent variable
Digital ulcers	−8.3	−14.8 to −1.8	0.013
Interstitial findings on HRCT	−9.8	−16.8 to −2.8	0.006
FVC	0.5	0.3 to 0.7	< 0.001
PH confirmed by RHC	−14.1	−26.8 to −1.5	0.028
TRV ≥ 2.9 m/s or other echo PH signs	− 14.9	−26.8 to −3.0	0.014

Only variables with statistical significance or tendency to be significant are presented

B regression coefficient, CI confidence interval, FVC forced vital capacity, HRCT high resolution computed tomography, ACA anticentromere antibodies, DLCO diffusion capacity of the lung for carbon monoxide, PAH pulmonary arterial hypertension, PH pulmonary hypertension, RHC right heart catheterization, TRV tricuspid regurgitation velocity