. Author manuscript; available in PMC: 2019 Aug 1.

Published in final edited form as: Expert Opin Ther Targets. 2018 Jul 26;22(8):675–686. doi: 10.1080/14728222.2018.1498845

Table1:

Antibodies to different domains of MUC16

MUC16 regions	Antibody	Immunogen	Predicted binding regions	References
N terminal Tandem Repeat	OC125	Purified CA125/ Cancer Cells	Tandem Repeats	8,42
	OC125			35,42
	M11			35,42
	M11			35,42
	OV197			35,42
	OV197			25
	VK8			25
	5E11	Tandem repeat	Tandem Repeats	34
	3A5	Purified CA125	Tandem repeat	134,135
MUC16 Carboxy terminus	5E6, 3H1	MUC16 carboxy terminus (114 amino acids)	Juxtamembrane domain	32
	2C6	MUC16 Cytoplasmic tail	MUC16 Cytoplasmic tail	33
	LUM16–4	MUC16 Cytoplasmic tail peptide	MUC16 Cytoplasmic Tail	36
	11D10	MUC16 extra cellular domain	82-amino acid sequence C-terminal to the mucin repeat domain	134,135