Table 1.
Patient demographic and clinical characteristics by colony-stimulating factor (CSF) use
| CSF Use | ||||
|---|---|---|---|---|
| Factor | Overall (N=13,203) |
Yes (N=5,266) |
No (N=7,937) |
P-value |
| N (%) | N (%) | N (%) | ||
| Year of Diagnosis | ||||
| 1992–1993 | 1,759 (13.3) | 318 (6.0) | 1,441 (18.2) | |
| 1994–1995 | 1,837 (13.9) | 673 (12.8) | 1,164 (14.7) | |
| 1996–1997 | 1,912 (14.5) | 827 (15.7) | 1,085 (13.7) | |
| 1998–1999 | 1,852 (14.0) | 800 (15.2) | 1,052 (13.3) | |
| 2000–2001 | 3,778 (28.6) | 1,841 (35.0) | 1,937 (24.4) | |
| 2002 | 2,065 (15.6) | 807 (15.3) | 1,258 (15.8) | <0.001 |
| Urban Residence | ||||
| No | 1,326 (10.0) | 407 (7.7) | 919 (11.6) | |
| Yes | 11,877 (90.0) | 4,859 (92.3) | 7,018 (88.4) | <0.001 |
| Age at Diagnosis | ||||
| Mean (SD) | 74.94 (6.35) | 74.38 (5.92) | 75.32 (6.59) | <0.001 |
| Median (Range) | 74 (65 – 102) | 74 (65 – 98) | 75 (65 – 102) | |
| 65–69 | 3,090 (23.4) | 1,276 (24.2) | 1,814 (22.9) | |
| 70–74 | 3,598 (27.3) | 1,548 (29.4) | 2,050 (25.8) | |
| 75–79 | 3,324 (25.2) | 1,389 (26.4) | 1,935 (24.4) | |
| 80–84 | 2,107 (16.0) | 744 (14.1) | 1,363 (17.2) | <0.001 |
| 85+ | 1,084 (8.2) | 309 (5.9) | 775 (9.8) | |
| Gender | ||||
| Male | 6,152 (46.6) | 2,469 (46.9) | 3,683 (46.4) | |
| Female | 7,051 (53.4) | 1,797 (53.1) | 4,254 (53.6) | 0.57 |
| Race/Ethnicity | ||||
| Non-Hispanic White | 11,776 (89.2) | 4,716 (89.6) | 7,060 (89.0) | |
| Hispanic | 236 (1.8) | 100 (1.9) | 136 (1.7) | |
| Black | 441 (3.3) | 155 (2.9) | 286 (3.6) | |
| Asian | 404 (3.1) | 176 (3.3) | 228 (2.9) | |
| Other | 304 (2.3) | 104 (2.0) | 200 (2.5) | |
| Unknown | 42 (0.3) | 15 (0.3) | 27 (0.3) | 0.04 |
| Marital Status | ||||
| Yes | 7,797 (59.1) | 3,291 (62.5) | 4,506 (56.8) | |
| No | 4,838 (36.6) | 1,778 (33.8) | 3,060 (38.6) | |
| Unknown | 568 (4.3) | 197 (3.7) | 371 (4.7) | <0.001 |
| SES Quartiles | ||||
| 1 (High) | 3,376 (25.6) | 1,396 (26.5) | 1,980 (24.9) | |
| 2 | 3,251 (24.6) | 1,349 (25.6) | 1,902 (24.0) | |
| 3 | 3,305 (25.0) | 1,249 (23.7) | 2,056 (25.9) | |
| 4 (Low) | 3,065 (23.2) | 1,189 (22.6) | 1,876 (23.6) | |
| Missing | 206 (1.6) | 83 (1.6) | 123 (1.5) | 0.007 |
| Histology | ||||
| Diffuse Large B-cell | 5,861 (44.4) | 2,538 (48.2) | 3,323 (41.9) | |
| Follicular | 2,428 (18.4) | 922 (17.5) | 1,506 (19.0) | |
| Other | 3,665 (27.8) | 1,384 (26.3) | 2,281 (28.7) | |
| Unknown | 1,249 (9.5) | 422 (8.0) | 827 (10.4) | <0.001 |
| Stage at Diagnosis | ||||
| I | 3,564 (27.0) | 1,336 (25.4) | 2,228 (28.1) | |
| II | 2,214 (16.8) | 888 (16.9) | 1,326 (16.7) | |
| III | 1,971 (14.9) | 888 (16.9) | 1,083 (13.6) | |
| IV | 4,519 (34.2) | 1,835 (34.8) | 2,684 (33.8) | |
| Unknown | 935 (7.1) | 319 (6.1) | 616 (7.8) | <0.001 |
| Comorbidity Score | ||||
| 0 | 8,216 (62.2) | 3,308 (62.8) | 4,908 (61.8) | |
| 1 | 3,148 (23.8) | 1,257 (23.8) | 1,891 (23.8) | |
| ≥2 | 1,839 (13.9) | 701 (13.3) | 1,138 (14.3) | 0.24 |