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. Author manuscript; available in PMC: 2019 Nov 2.
Published in final edited form as: Expert Rev Vaccines. 2018 Nov 2;17(11):967–976. doi: 10.1080/14760584.2018.1541408

Fig. 2. New double-layered protein nanoparticles from influenza conserved antigens.

Fig. 2.

The soluble recombinant conserved influenza antigens are purified from baculovirus-based insect cell protein expression system. Multivalent antigenic nanoparticles are generated by coating conserved influenza surface antigens and/or adjuvant proteins onto desolvated (M2e+NP) nanoparticle cores as an outer layer.