Table 3. Characteristics of the economic evaluations.
| Study [Reference] | Study type | Time horizon | Perspective | ICER (EUR 2016) | CHEC |
|---|---|---|---|---|---|
| Surgery compared to non-surgical initial treatment | |||||
| Chronic anterior cruciate ligament injury | |||||
| Gottlob et al [26] | Model-based CUA | Seven years | N/A | 7.730 per QALY | 53% |
| Mather III et al [27] | Trial-based CUA | Model 1: Six years Model 2: lifetime |
Societal | Model 1: Cost saving of 4.240 and QALY gain of 0.18. Model 2: Cost saving of 47.474 and QALY gain of 0.72. |
79% |
| Mather III et al [28] | Trial-based CUA | Six years | Societal | ER group: 3.713 per QALY DR group: 4.242 per QALY |
74% |
| Stewart et al [29] | Model-based CUA | Six years | Societal | 20.778 per QALY | 84% |
| Farshad et al [30] | Model-based CUA | 90 months | Third party payers | 4.815 per QALY | 53% |
| Kiadaliri et al [31] | Trial-based CUA | Five years | Societal | Early ACL: 25.686 and 3,96 QALY Optional delayed ACL group: 21.060 and 3,83 QALY. |
84% |
| Bierbaum et al [32] | Model-based CUA | Three years | The community of insured citizens. | 9,092.66 per QALY | 68% |
| Surgery compared to surgery management | |||||
| Cartilage defects | |||||
| Derrett et al [33] | Model-based CUA | Two years | N/A | 28.723 per QALY | 58% |
| Elvidge et al [34] | Trial-based CEA | 75 years | NHS | 28.788 per QALY | 89% |
| Gerlier et al [35] | Trial-based CUA | 40 years | Global healthcare payer perspective | 18.073 per QALY | 84% |
| Traumatic meniscus injury | |||||
| Rongen et al [36] | Model-based CUA | Model 1: lifetime Model 2: five years |
Societal | 297.727 per QALY. | 84% |
| Ramme et al [37] | Model-based CEA | 25 years | Healthcare system | 771 per-year-gained in time to TKA. | 79% |
| Anterior cruciate ligament injury | |||||
| Paxton et al [38] | Model-based CUA | 12 years postoperatively | Societal | 6.420 per QALY | 68% |
| Genuario et al [39] | Model-based CUA | One year | Societal | HS: 5.140 and 0,912 QALY BPTB: 4.917 and 0,966 QALY Allografts: 6.656 and 0,904 QALY |
79% |
| Exercise compared to usual care | |||||
| Patellofemoral pain syndrome | |||||
| Tan et al [40] | Trial-based CUA | One year | Societal and healthcare | 16.299 saving per QALY gained | 79% |
ACL: anterior cruciate ligament, BPTB: bone-patellar-tendon-bone, CEA: cost-effectiveness analysis, CUA: cost-utility analysis, HS: hamstring, ICER: incremental cost-effectiveness ratio, N/A: not applicable, TKA: total knee arthroplasty, QALY: quality-adjusted life year.