Table S1.

Effect of Al-hijamah (wet cupping therapy of prophetic medicine) as an effective PIET in reducing iron overload and oxidative stress with subsequent increase in TAC

Patient no	Serum ferritin (ng/mL)		Serum malondialdehyde (nM/L)		Mean TAC (mM/L)
	Before Al-hijamah	After Al-hijamah	Before Al-hijamah	After Al-hijamah	Before Al-hijamah	After Al-hijamah
1	2,864	1,426	29.5	14	0.23	0.59
2	1,407	1,005	30.9	19.1	0.4	0.67
3	1,000	977	25.5	12.2	0.35	0.55
4	3,215	2,712	27.9	13.9	0.32	0.72
5	2,105	1,900	22.2	7	0.15	0.51
6	7,251	6,120	28.5	14.2	0.29	0.72
7	2,799	2,182	50.1	19.6	0.27	0.6
8	9,210	8,530	32.2	15	0.23	0.59
9	2,210	1,148	30.1	14.9	0.39	0.7
10	3,316	1,990	29.5	7.4	0.28	0.63
11	4,200	400	22.5	7.6	0.14	0.61
12	2,325	1,870	32.5	19.9	0.28	0.56
13	3,400	2,241	277	12.5	0.14	0.73
14	7,527	6,692	29.3	13.5	0.28	0.58
15	1,988	1,065	30.9	11.3	0.15	0.83
16	3,215	2,398	26.8	14.8	0.22	0.77
17	2,799	2,182	32.2	15.1	0.15	0.8
18	9,210	8,530	27.9	7.9	0.31	0.69
19	2,210	1,148	25.6	10	0.26	0.8
20	3,316	1,990	32	14	0.27	0.69
Mean	3,778.35	2,825.3	42.155	13.195	0.2555	0.667
SD	2,466.986853	2,499.65789	55.56347224	3.85725222	0.07983370	0.0925145
SEM	551.8986249	559.207582	12.43030699	0.86291996	0.01785989	0.0206967

Abbreviations: PIET, percutaneous iron excretion therapy; TAC, total antioxidant capacity; SEM, standard error of mean.