Table 3.
Genotype and allele frequency distribution of rs6000782 and rs1799724 in pAIH patients and controls.
| Genotypes and alleles | pAIH n = 56 (%) |
Controls n = 44 (%) | OR | 95% CI | P value | |
|---|---|---|---|---|---|---|
| rs6000782 A/C | AA | 31 (55.36) | 32 (72.73) | Ref | ||
| AC | 19 (33.93) | 12 (27.27) | 1.63 | 0.68–3.92 | 0.283 | |
| CC | 6 (10.71) | 0 (0) | – | – | 0.027* | |
| AC + CC | 25 (44.64) | 12 (27.27) | 2.15 | 0.92–5.02 | 0.096 | |
| AA + AC | 50 (89.29) | 44 (100) | Ref | |||
| CC | 6 (10.71) | 0 (0) | – | – | 0.033* | |
| Allele A | 81 (72.3) | 76 (86.4) | Ref | |||
| Allele C | 31 (27.7) | 12 (13.6) | 2.42 | 1.16–5.06 | 0.023* | |
| rs1799724 C/T | CC | 31 (55.36) | 35 (79.55) | Ref | ||
| CT | 22 (39.28) | 9 (20.45) | 2.76 | 1.11–6.88 | 0.031* | |
| TT | 3 (5.36) | 0 (0) | – | – | 0.114 | |
| CT + TT | 25 (44.64) | 9 (20.45) | 3.14 | 1.27–7.73 | 0.019* | |
| CC + CT | 53 (94.64) | 44 (100) | Ref | |||
| TT | 3 (5.36) | 0 (0) | – | – | 0.253 | |
| Allele C | 84 (75) | 79 (89.77) | Ref | |||
| Allele T | 28 (25) | 9 (10.23) | 2.93 | 1.30–6.59 | 0.010* | |
Values are expressed as numbers (percentages). CI, confidence interval; Ref, reference.
*
Indicates statistical significance (P < 0.05).