Table 1.
Clinical baseline, interventional and outcome characteristics.
| Tandem intracranial-extracranial occlusions (N = 121) | Isolated intracranial occlusions (N = 456) | P | |
|---|---|---|---|
| BASELINE | |||
| Age (years) | 72 (61–79) | 70 (63–78) | 0.544 |
| Sex, female | 25.6% (31/121) | 50.4% (230/456) | < 0.001 |
| Admission NIHSS | 17 (IQR 12–20) | 16 (IQR 13–21) | 0.474 |
| IVT | 52.1% (63/121) | 53.9% (246/456) | 0.759 |
| Intracranial occlusion site | 0.003 | ||
| - M1 | 67.8% (82/121) | 80.9% (369/456) | |
| - ICA | 32.2% (39/121) | 19.1% (87/456) | |
| Symptom-onset to groin puncture (mins) | 262 (IQR 194–356) | 241 (IQR 190–315) | 0.093 |
| Atrial fibrillation | 30.0% (36/120) | 45.2% (192/425) | 0.003 |
| Diabetes | 20.7% (25/121) | 13.6% (62/455) | 0.063 |
| Arterial hypertension | 62.8% (76/121) | 65.2% (296/454) | 0.669 |
| Dyslipidemia | 51.3% (61/119) | 45.9% (208/453) | 0.304 |
| Smoking | 45.8% (54/118) | 24.2% (102/421) | < 0.001 |
| INTERVENTIONAL | |||
| Procedure time | 57 (IQR 87–115) | 33 (IQR 49–89) | < 0.001 |
| Number of maneuvers | 1 (IQR 1–3) | 1 (IQR 1–3) | 0.495 |
| Final TICI 2b/3 | 70.2% (85/121) | 83.6% (381/456) | 0.002 |
| Complications | 0.122 | ||
| - None - Dissection - Perforation - Other |
- 89.3% (108/121) - 7.4% (9/121) - 2.5% (3/121) - 0.8% (1/121) |
- 93.2% (425/456) - 5.7% (26/456) - 0.4% (2/456) - 0.7% (3/456) |
|
| Infarct in previously unaffected territories | 7.4% (9/121) | 8.6% (39/456) | 0.853 |
| OUTCOME | |||
| sICH | 10.7% (13/121) | 6.9% (31/452) | 0.177 |
| aICH | 29.8% (36/121) | 17.09% (77/452) | 0.003 |
| 90-day mRS | 3 (IQR 1–4) | 3 (IQR 1–4) | 0.142 |
| 90-day mRS ≤ 2 | 42.4% (50/118) | 49.6% (212/427) | 0.177 |
| 90-day mortality | 19.5% (23/118) | 15.7% (67/427) | 0.329 |