Table 2.

Pooled HRs and 95%CIs from the meta-analysis for OS.

Non-coding RNA	Model	No. of studies	No. of patients	HR (95%CI)	P-value	Heterogeneity (%)	(I2, P-value)
let-7i(rs10877887)	CT+CC vs. TT	2	420	1.32 (1.09, 1.60)	0.004	0.0	0.307
Let-7a-1(rs10739971)	GA vs. GG	2	1,095	1.01 (0.84, 1.21)	0.942	0.0	0.384
	AA vs. GG	2	1,095	0.87 (0.46, 1.64)	0.666	72.0	0.557
	GA+AA vs. GG	2	1,095	1.04 (0.86, 1.26)	0.655	0.0	0.557
let-7a-2(rs629367)	AC vs. AA	3	1,834	1.07 (0.76, 1.50)	0.694	70.90	0.016
	CC vs. AA	2	1,684	0.92 (0.64, 1.33)	0.666	0.0	0.747
	AC+CC vs. AA	2	1,684	0.93 (0.79, 1.09)	0.368	0.0	0.467
miR-218(rs11134527)	AG vs. AA	2	362	1.02 (0.82, 1.28)	0.856	0.0	0.356
	GG vs. AA	2	362	0.84 (0.61, 1.15)	0.284	46.9	0.170
	AG+GG vs. AA	2	249	0.89 (0.51, 1.54)	0.673	58.3	0.122
	GG vs. AG+AA	2	362	0.91 (0.54, 1.54)	0.733	60.5	0.112
mir-26a-1(rs7372290)	CT vs. CC	2	892	1.17 (0.96, 1.42)	0.117	0.0	0.975
	TT vs. CC	2	892	1.07 (0.77, 1.49)	0.677	0.0	0.874
miR-27a(rs895819)	CT vs. TT	3	1,526	1.28 (0.92, 1.79)	0.149	67.4	0.046
	CC vs. TT	3	1,526	1.25 (0.98, 1.59)	0.071	31.7	0.231
	CT+CC vs. TT	4	1,588	1.23 (0.86, 1.76)	0.254	51.1	0.105
	CC vs. CT+TT	2	950	1.09 (0.84, 1.41)	0.513	0.0	0.341
miR-34b/c(rs4938723)	TC+CC vs. TT	2	892	0.91 (0.75, 1.14)	0.338	0.0	0.845
	CC vs. TC+TT	2	2,103	0.69 (0.48, 1.00)	0.047	0.0	0.656
miR-423(rs6505162)	AC vs. CC	5	1,470	1.25 (0.91, 1.72)	0.176	56.1	0.059
	AA vs. CC	5	1,470	1.00 (0.73, 1.37)	0.990	0.0	0.406
	AC+AA vs. CC	2	604	1.20 (0.38, 3.76)	0.610	89.6	0.002
	AA vs. AC+CC	2	604	1.10 (0.53, 2.28)	0.789	0.0	0.485
miR-492(rs2289030)	GC vs. CC	2	768	0.73 (0.56, 0.94)	0.014	0.0	0.963
	GG vs. CC	2	768	0.88 (0.64, 1.20)	0.415	0.0	0.643
	GG vs. CG+CC	2	768	0.94 (0.69, 1.27)	0.676	0.0	0.532
	GC+GG vs. CC	2	768	0.74 (0.58, 0.94)	0.014	0.0	0.848
miR-499(rs3746444)	CT vs. TT	6	1,813	1.01 (0.85, 1.20)	0.896	0.0	0.554
	CC vs. TT	5	1,746	0.96 (0.61,1.51)	0.864	0.0	0.789
	CC vs. CT+TT	2	770	0.75 (0.33, 1.71)	0.498	0.0	0.484
	CT+CC vs. TT	2	567	1.14 (0.77, 1.68)	0.505	0.0	0.399
	TT vs. CT+CC	2	1,277	0.65 (0.49, 0.85)	0.002	43.5	0.184
miR-608(rs4919510)	CG vs. GG	4	1,858	0.81 (0.70, 0.94)	0.004	24.1	0.267
	CC vs. GG	4	1,858	0.84 (0.63, 1.13)	0.248	54.3	0.087
	CG vs. CC	2	441	1.14 (0.82,1.60)	0.434	0.0	0.542
	GG vs. CC	2	441	1.32 (0.77, 2.26)	0.317	0.0	0.794
	CC vs. CG+GG	3	966	0.71 (0.55, 0.93)	0.013	0.0	0.978
	CG+CC vs.GG	3	966	0.74 (0.59, 0.93)	0.009	0.0	0.778
miR-30c(rs928508)	AG+GG vs. AA	2	1,015	1.14 (0.43, 2.98)	0.793	88.0	0.004
miR-378(rs1076064)	AG vs. AA	2	1,254	0.83 (0.69, 0.98)	0.032	0.0	0.378
	GG vs. AA	2	1,254	0.72 (0.45, 1.16)	0.180	79.9	0.007
let-7a-1(rs10739971)	GA vs. GG	2	1,095	1.01 (0.73, 1.40)	0.934	0.0	0.567
	GA+AA vs. GG	2	1,095	1.04 (0.77, 1.42)	0.782	0.0	0.715
miR-146(rs2910164)	CG vs. CC	6	2,244	0.98 (0.86, 1.13)	0.820	0.0	0.805
	GG vs. CC	8	2,805	1.03 (0.86, 1.23)	0.758	23.8	0.240
	GC vs. GG	2	561	0.94 (0.68, 1.30)	0.728	0.0	0.377
	GC+GG vs. CC	5	1,357	0.84 (0.55, 1.30)	0.436	51.9	0.081
	GG vs. GC+CC	7	3,360	0.92 (0.70, 1.21)	0.549	57.4	0.029
miR-149(rs2292832)	CT vs. TT	5	1,581	0.77 (0.66, 0.91)	0.002	0.0	0.516
	CC vs. TT	6	2,244	0.71 (0.57, 0.88)	0.002	42.3	0.123
	CT+CC vs. TT	6	2,244	0.76 (0.67, 0.86)	<0.001	9.5	0.355
	CC vs. CT+TT	5	2,335	0.62 (0.52, 0.74)	<0.001	0.0	0.472
miR-196a2(rs11614913)	CT vs. TT	7	2,371	1.12 (0.89, 1.41)	0.335	40.6	0.121
	CC vs. TT	6	2,192	1.14 (0.75, 1.73)	0.548	67.8	0.008
	CT+CC vs. TT	6	1,439	1.28 (0.85, 1.93)	0.247	63.3	0.018
	CC vs. CT+TT	7	3,836	0.92 (0.67, 1.24)	0.572	79.4	< 0.001
	TC vs. CC	3	645	0.77 (0.60, 1.00)	0.048	0.0	0.568
	TT vs. CC	3	645	0.83 (0.58, 1.19)	0.304	0.0	0.848
	TC+TT vs. CC	2	644	0.62 (0.46, 0.85)	0.003	49.8	0.158
	TT vs. TC+CC	2	432	0.92 (0.50, 1.70)	0.787	76.5	0.029

OS, overall survival; HR, hazard ratio; CI, confidence interval. Bolded values are expressed as values of statistical significance.