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. 2018 Dec 13;8:596. doi: 10.3389/fonc.2018.00596

Table 3.

Pooled HRs and 95%CIs from the meta-analysis of RFS.

Non-coding RNA Model No. of studies No. of patients HR (95%CI) P-value Heterogeneity (%) (I2, P-value)
miR-27a(rs895819) CT vs. TT 3 1,388 1.00 (0.83, 1.22) 0.963 23.7 0.270
CC vs. TT 3 1,388 0.92 (0.72, 1.17) 0.483 0.0 0.827
CT+CC vs.TT 4 1,400 0.99 (0.84, 1.18) 0.921 0.0 0.413
CC vs. CT+TT 2 950 0.90 (0.71, 1.14) 0.373 0.0 0.933
miR-423(rs6505162) AC vs. CC 3 925 1.34 (1.03, 1.73) 0.026 24.1 0.268
AA vs. CC 3 925 0.89 (0.47, 1.70) 0.730 0.0 0.870
AC+AA vs. CC 2 796 1.37 (1.01, 1.86) 0.042 29.0 0.235
miR-492(rs2289030) GG vs. CC 2 796 1.10 (0.56, 2.15) 0.785 0.0 0.438
GG vs. GC+CC 2 796 0.98 (0.65, 1.46) 0.910 0.0 0.894
miR-608(rs4919510) CG vs. GG 2 912 0.73 (0.60, 0.88) 0.001 0.0 0.401
CC vs. GG 2 912 0.82 (0.49, 1.35) 0.429 0.0 0.128
miR-146(rs2910164) GC vs. CC 2 795 0.84 (0.57, 1.26) 0.400 60.4 0.080
GG vs. CC 3 1,203 0.89 (0.66, 1.21) 0.462 37.1 0.189
GG vs. GC+CC 3 889 0.89 (0.56, 1.40) 0.608 60.8 0.078
GC+GG vs. CC 2 795 0.79 (0.35, 1.78) 0.570 83.0 0.015
CC vs. GC+GG 2 751 1.37 (0.59, 3.20) 0.470 82.1 0.018
miR-196a2(rs11614913) CT vs. TT 2 795 0.71 (0.49, 1.03) 0.074 0.0 0.715
CC vs. TT 2 795 0.84 (0.54, 1.29) 0.423 0.0 0.369
CT+CC vs. TT 2 795 0.76 (0.53, 1.08) 0.123 0.0 0.513

RFS, relapse-free survival; HR, hazard ratio; CI, confidence interval. Bolded values are expressed as values of statistical significance.