Table 3.
Non-coding RNA | Model | No. of studies | No. of patients | HR (95%CI) | P-value | Heterogeneity (%) | (I2, P-value) |
---|---|---|---|---|---|---|---|
miR-27a(rs895819) | CT vs. TT | 3 | 1,388 | 1.00 (0.83, 1.22) | 0.963 | 23.7 | 0.270 |
CC vs. TT | 3 | 1,388 | 0.92 (0.72, 1.17) | 0.483 | 0.0 | 0.827 | |
CT+CC vs.TT | 4 | 1,400 | 0.99 (0.84, 1.18) | 0.921 | 0.0 | 0.413 | |
CC vs. CT+TT | 2 | 950 | 0.90 (0.71, 1.14) | 0.373 | 0.0 | 0.933 | |
miR-423(rs6505162) | AC vs. CC | 3 | 925 | 1.34 (1.03, 1.73) | 0.026 | 24.1 | 0.268 |
AA vs. CC | 3 | 925 | 0.89 (0.47, 1.70) | 0.730 | 0.0 | 0.870 | |
AC+AA vs. CC | 2 | 796 | 1.37 (1.01, 1.86) | 0.042 | 29.0 | 0.235 | |
miR-492(rs2289030) | GG vs. CC | 2 | 796 | 1.10 (0.56, 2.15) | 0.785 | 0.0 | 0.438 |
GG vs. GC+CC | 2 | 796 | 0.98 (0.65, 1.46) | 0.910 | 0.0 | 0.894 | |
miR-608(rs4919510) | CG vs. GG | 2 | 912 | 0.73 (0.60, 0.88) | 0.001 | 0.0 | 0.401 |
CC vs. GG | 2 | 912 | 0.82 (0.49, 1.35) | 0.429 | 0.0 | 0.128 | |
miR-146(rs2910164) | GC vs. CC | 2 | 795 | 0.84 (0.57, 1.26) | 0.400 | 60.4 | 0.080 |
GG vs. CC | 3 | 1,203 | 0.89 (0.66, 1.21) | 0.462 | 37.1 | 0.189 | |
GG vs. GC+CC | 3 | 889 | 0.89 (0.56, 1.40) | 0.608 | 60.8 | 0.078 | |
GC+GG vs. CC | 2 | 795 | 0.79 (0.35, 1.78) | 0.570 | 83.0 | 0.015 | |
CC vs. GC+GG | 2 | 751 | 1.37 (0.59, 3.20) | 0.470 | 82.1 | 0.018 | |
miR-196a2(rs11614913) | CT vs. TT | 2 | 795 | 0.71 (0.49, 1.03) | 0.074 | 0.0 | 0.715 |
CC vs. TT | 2 | 795 | 0.84 (0.54, 1.29) | 0.423 | 0.0 | 0.369 | |
CT+CC vs. TT | 2 | 795 | 0.76 (0.53, 1.08) | 0.123 | 0.0 | 0.513 |
RFS, relapse-free survival; HR, hazard ratio; CI, confidence interval. Bolded values are expressed as values of statistical significance.