Table 5.
Pooled HRs and 95%CIs from the meta-analysis of stratified data.
| Variables | Non-coding RNA | Model | No. of studies | No. of patients | Outcome | HR (95%CI) | P-value | Heterogeneity (%) | (I2, P-value) |
|---|---|---|---|---|---|---|---|---|---|
| GENDER | |||||||||
| Male | miR-196a(rs11614913) | CT+TT vs. CC | 2 | 704 | OS | 1.75 (0.52, 2.65) | 0.698 | 87.0 | 0.006 |
| Female | miR-196a(rs11614913) | CT+TT vs. CC | 2 | 239 | OS | 0.77 (0.17, 3.51) | 0.730 | 85.3 | 0.009 |
| SMOKING | |||||||||
| Ever | miR-196a(rs11614913) | CT+TT vs. CC | 2 | 1,024 | OS | 0.90 (0.68, 1.19) | 0.452 | 38.5 | 0.202 |
| miR-196a(rs11614913) | CT+TT vs. CC | 2 | 335 | DFS | 0.88 (0.52, 1.44) | 0.584 | 80.6 | 0.023 | |
| Never | miR-196a(rs11614913) | CT+TT vs. CC | 2 | 1,024 | OS | 0.48 (0.29, 0.90) | 0.005 | 0.0 | 0.819 |
| miR-196a(rs11614913) | CT+TT vs. CC | 2 | 335 | DFS | 0.54 (0.35, 0.84) | 0.007 | 0.0 | 0.667 | |
OS, overall survival; DFS, disease-free survival; HR, hazard ratio; CI, confidence interval. Bolded values are expressed as values of statistical significance.